Chonnam Med J.  1995 Jun;31(1):123-130.

A Study for the Control of Hospital Infection: Epidemiologic study of methicillin-resistant Staphyloccus aureus

• Song KY
• Moon KH
• Ko M
• Yoo HJ
• Choi SY
• Park YN
• Cho KH
• Kim SH
• Ryang DW

Abstract

BACKGROUND: Methicillin-resistant Staphyloccus aureus (MRSA) has become a major nosocomial pathogen in community hospitals and tertiary care hospitals. But, there was a few report of epidemiologic study for the control or nosocomial infection not only Chonnam University Hospital (CUH) but also in Korea. Thus, we performed this study to evaluate the rate of isolation of MRSA in the clinical specimens for recent 2 years.
METHODS
We analysed total 2,308 strains of S. aurens, isolated from the clinical specimens, The resistance to methicillin was tested by Kirby-Bauer method using, 1microgram oxacillin disc and determination of susceptibility was carried out according to the recommendation of the National Committee for Clinical Laboratory Standards (NCCLS).
RESULTS
The rate of isolation of MRSA was 69.1% in clinical specimens. But, the change of the rate of isolation was not found recent 2 years. The most high rate of isolation was observed in respiratory specimens 85.1%. Intensive care unit (ICU), where 74.3% of isolates are methicillin resistant, was the most prevalent area of MRSA in CUH.
CONCLUSION
These results suggest that there are significant nosocomial infections in the hospital, especially in ICU. We recommend that more appropriate control measure and control efforts for the prevention of nosocomial infection, especially MRSA, are required in CUH.

Keyword

Nosocomial infection; MRSA

MeSH Terms

Cross Infection*
Epidemiologic Studies*
Hospitals, Community
Intensive Care Units
Jeollanam-do
Korea
Methicillin
Methicillin Resistance*
Methicillin-Resistant Staphylococcus aureus
Oxacillin
Tertiary Healthcare
Methicillin
Oxacillin