Chonnam Med J.  2012 Aug;48(2):86-90. 10.4068/cmj.2012.48.2.86.

Clinicopathological Features of Female Gastric Carcinoma Patients with Curative Resection: Comparison with Male Patients

• Kim HG
• Ghu HD
• Yun SK
• Ryu SY
• Kim DY

• KMID: 2172208
• DOI: http://doi.org/10.4068/cmj.2012.48.2.86

Abstract

Little is known about the clinicopathological features of female gastric carcinoma (FGC) patients. We compared the clinicopathologic features and outcomes of FGC patients with curative resection with those of male gastric carcinoma (MGC) patients. We reviewed the hospital records of 940 FGC patients between 1986 and 2005 at Chonnam National University Hospital. Multivariate analysis showed that presence of serosal invasion, lymph node metastasis, and operative type were significant prognostic factors for survival of FGC patients with curative resection. Furthermore, the overall 5-year survival rate of FGC patients with curative resection (53.4%) was higher than that of MGC patients (47.6%, p<0.05). In advanced cases, no significant difference was observed in the overall 5-year survival rate between the FGC and MGC patients (41.6% vs 37.4%, p>0.05). Therefore, serosal invasion, lymph node metastasis, and type of operation were statistically significant parameters associated with survival. Early detection is more important for improving the prognosis of female patients with gastric cancer than for male patients.

Keyword

Female gastric carcinoma; Prognosis; Early detection of cancer

MeSH Terms

Early Detection of Cancer
Female
Hospital Records
Humans
Lymph Nodes
Male
Multivariate Analysis
Neoplasm Metastasis
Prognosis
Stomach Neoplasms
Survival Rate

Figure

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  FIG. 1 Survival curves of female and male gastric carcinoma patients with curative resection (male=47.6% vs. female= 53.4%) (p=0.010). F: female, M: male.

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  FIG. 2 Survival curves of early female and early male gastric carcinoma (overall 5-year survival rate; male=86.12%, female=94.31%) (p=0.046). F: female, M: male.

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  FIG. 3 Survival curves of advanced female and advanced male gastric carcinoma patients with curative resection (male=37.4% vs. female=41.6%) (p=0.077). F: female, M: male.

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