Ann Dermatol.
2006 Jun;18(1):37-39. 10.5021/ad.2006.18.1.37.
A Case of Palisaded Encapsulated Neuroma of the Lower Lip
- Affiliations
-
- 1Department of Dermatology, Chosun University Medical School, Gwangju, Korea. bsjung@ chosun.ac.kr
- KMID: 2172105
- DOI: http://doi.org/10.5021/ad.2006.18.1.37
Abstract
- Palisaded encapsulated neuroma (PEN) is a clinically-distinctive, benign, cutaneous nerve sheath tumor. It usually occurs as a solitary, asymptomatic, skin-colored papule, and commonly affects the face of middle-aged adults. We report a case of PEN which developed on the lower lip of a 44-year-old Korean man. It was a 5mm-sized skin colored papule. Histopathologically, it consisted of uniform, broad, interlacing fascicles of spindle cells and was surrounded by a complete capsule in the dermis. On immunohistochemical staining, the tumor cells of the nodule were positive for S-100 protein and neural filaments, whil the capsule of the nodule was positive for epithelial antigen.
