Ann Dermatol.  2008 Jun;20(2):67-69. 10.5021/ad.2008.20.2.67.

A Case of Digital Myxoid Cyst Coexisting with Epidermal Inclusion Cyst

Affiliations
  • 1Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea. drkmp@hanmail.net
  • 2Department of Dermatology, School of Medicine, Kyungpook National University, Daegu, Korea.

Abstract

A 62-year-old male developed a solitary asymptomatic nodule on the lateral aspect of the distal interphalangeal joint of the right great toe. Histopathologic findings demonstrated a myxoid cyst with a concomitant epidermal inclusion cyst. To the best of our knowledge, this is the first case of concurrent occurrence of digital myxoid cyst and epidermal inclusion cyst. Although the exact mechanism for developing a digital myxoid cyst and an epidermal inclusion cyst simultaneously at the same site is not explained, trauma might be a possible cause.

Keyword

Digital myxoid cyst; Epidermal inclusion cyst; Co-occurrence

MeSH Terms

Ganglion Cysts
Humans
Joints
Male
Middle Aged
Toes

Figure

  • Fig. 1 Solitary dome-shaped nodule measuring 0.8×0.9 cm on the lateral aspect of distal phalanx of the great toe.

  • Fig. 2 (A) Histopathologic findings show a cystic lesion lined by keratinizing stratified squamous epithelium compatible with epidermal inclusion cyst (H&E stain, original magnification ×40). (B, C) Myxoid materials around epidermal inclusion cyst shows the presence of abundant mucin (Alcian blue 2.5 stain (B) and Colloidal iron stain (C), original magnification, ×100 (B), original magnification, ×200 (C)).


Reference

1. Heenan PJ. Tumors of fibrous tissue involving the skin. In : Elder DE, Elenitsas R, Johnson B, Murphy GF, editors. Lever's histopathology of the skin. 9th ed. Philadelphia: Lippincott-Raven;2004. p. 1003–1004.
2. Fisher BK, Macpherson M. Epidermoid cyst of the sole. J Am Acad Dermatol. 1986; 15:1127–1129.
Article
3. Armijo M. Mucoid cysts of the fingers. Differential diagnosis, ultrastructure, and surgical treatment. J Dermatol Surg Oncol. 1981; 7:317–322.
Article
4. Salasche SJ. Myxoid cysts of the proximal nail fold: a surgical approach. J Dermatol Surg Oncol. 1984; 10:35–39.
Article
5. de Berker D, Lawrence C. Ganglion of the distal interphalangeal joint (myxoid cyst): therapy by identification and repair of the leak of joint fluid. Arch Dermatol. 2001; 137:607–610.
6. Drape JL, Idy-Peretti I, Goettmann S, Salon A, Abimelec P, Guerin-Surville H, et al. MR imaging of digital mucoid cysts. Radiology. 1996; 200:531–536.
Article
7. Johnson WC, Graham JH, Helwig EB. Cutaneous myxoid cyst. A clinicopathological and histochemical study. JAMA. 1965; 191:15–20.
8. Johnson WC, Helwig EB. Cutaneous focal mucinosis. A clinicopathological and histochemical study. Arch Dermatol. 1966; 93:13–20.
Article
9. Golitz LE, Poomeechaiwong S. Cysts. In : Farmer ER, Hood AF, editors. Pathology of the skin. New Jersey: Prentice Hall;1990. p. 511–531.
10. Epstein WL, Kligman AM. Epithelial cysts in buried human skin. AMA Arch Derm. 1957; 76:437–445.
Article
11. Takeda H, Miura A, Katagata Y, Mitsuhash Y, Kondo S. Hybrid cyst: case reports and review of 15 cases in Japan. J Eur Acad Dermatol Venereol. 2003; 17:83–86.
Article
12. Wang WC, Lin LM, Shen YH, Lin YJ, Chen YK. Concurrent extravasation mucocele and epidermoid cyst of the lower lip: a case report. Kaohsiung J Med Sci. 2005; 21:475–479.
Article
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