Ann Dermatol.  2015 Aug;27(4):435-438. 10.5021/ad.2015.27.4.435.

Multiple Segmental Eccrine Spiradenoma with a Zosteriform Pattern: A Case Report and Literature Review

Affiliations
  • 1Southern Medical University, Nanjing, China. sanghong@nju.edu.cn
  • 2Department of Dermatology, Jinling Hospital, Nanjing University of Medicine, Nanjing, China.

Abstract

Eccrine spiradenoma usually occurs as solitary tender nodules. However, it rarely occurs as multifocal localized tumors or has zosteriform distribution. We report the case of a 32-year-old woman with a 20-year history of itchy lesions on the left side of the back and forearm with a zosteriform distribution. Before disease onset, almost no patients have inducing factors, but our patient received an injection beforehand; however, whether this was coincidental or causative remains unknown. The lesions became very itchy after perspiration or eating spicy food, which has never been reported. A literature search revealed 22 cases of multiple segmental eccrine spiradenoma; we summarized the clinical characteristic in order to aid diagnosis and treatment selection.

Keyword

Eccrine spiradenoma; Itchy; Multiple; Zosterifrom

MeSH Terms

Adult
Diagnosis
Eating
Female
Forearm
Humans

Figure

  • Fig. 1 Zosteriform dermal nodules on the back and forearm.

  • Fig. 2 (A) Multiple well-circumscribed dermal nodules comprising basophilic cells in the deep dermis. The basaloid cells are arranged in a trabecular pattern with eosinophilic fibrous strands (H&E, ×40). (B) High-powered view demonstrating small dark basaloid cells with hyperchromatic nuclei, larger cells with pale nuclei in the center of the clusters, and numerous lymphocytes scattered throughout (H&E, ×400).


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