Ann Dermatol.  2015 Oct;27(5):643-645. 10.5021/ad.2015.27.5.643.

A Giant, Deep, Benign Fibrous Histiocytoma with a Palisading Pattern

• Kang JN
• Lee W
• Jung SY
• Jung SW
• Seol JE
• Kim H
• Sung HS

• KMID: 2171479
• DOI: http://doi.org/10.5021/ad.2015.27.5.643

Abstract

No abstract available.

MeSH Terms

Histiocytoma, Benign Fibrous*

Figure

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  Fig. 1 (A) A skin-colored mass on the back (arrows) with a coincident overlying skin tag (inset: close-up view). (B) The excised 5×5×2 cm well-encapsulated erythematous oval mass.

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  Fig. 2 (A) Scanning view of the histopathological examination of the lesion showing an encapsulated mass located from the lower dermis through the subcutaneous tissue with a central cavity. The tumor was well circumscribed by a fibrous capsule, and no honeycomb pattern was detected in the marginal area. Hemangiopericytoma-like dilated vessels were seen in the periphery of the tumor (H&E, ×5). (B) Tumor cells arranged in a palisading pattern, similar to that of Verocay bodies, with a focal storiform pattern and partial myxoid change (H&E, ×40). (C) Spindle-shaped tumor cells with elongated nuclei and an ill-defined cytoplasm. Neither cellular atypia nor mitotic bodies were detected (H&E, ×400). Immunohistochemical staining showed (D) a strong positivity to CD34 (×40) and (E) negativity to S-100 (×40).

Reference

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