Ewha Med J.  2015 Mar;38(1):50-53. 10.12771/emj.2015.38.1.50.

Gastric Involvement of Pulmonary Sarcoidosis

• Hong SH
• Chang JY
• Chung MK
• Son HM
• Tae CH
• Chang JH
• Shim KN

• KMID: 2171330
• DOI: http://doi.org/10.12771/emj.2015.38.1.50

Abstract

Gastric sarcoidosis is a rare disease accounting for 0.1~0.9% of all sarcoidosis cases. It presents either as a systemic disease or as an isolated finding. Diagnosis is established with biopsy of a lesion. It is important to distinguish between sarcoidosis and a sarcoid-like reaction, which can be caused by Crohn's disease, foreign body reaction, fungal infection, tuberculosis, or malignancy. We report a 60-year-old woman with both gastric and pulmonary sarcoidosis.

Keyword

Sarcoidosis; Stomach; Granulomatous gastritis

MeSH Terms

Biopsy
Crohn Disease
Diagnosis
Female
Foreign-Body Reaction
Humans
Middle Aged
Rare Diseases
Sarcoidosis
Sarcoidosis, Pulmonary*
Stomach
Tuberculosis

Figure

• 

  Fig. 1 Computed tomography of chest and abdomen. (A) In lung setting view, an interlobular and peribronchovascular septal thickening is noted. Also there is fibrosis at right basal lung (arrow). (B) The enlarged lymph nodes are observed along the left gastric artery, splenic artery, gastrocolic trunk, and great omentum (arrow). There is no mass or thickening in the walls of the stomach.

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  Fig. 2 Esophagogastroduodenoscopy and pathologic finding of stomach biopsy. (A) The mucosal depression (0.8 cm) is seen in the greater curvature side of lower body (arrow). (B) There are multinucleated giant cells and some of them contain Schaumann bodies in the cytoplasm (arrow) (H&E, ×200).

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  Fig. 3 Pathologic findings of abdominal lymph node biopsy. (A) Numerous, closely packed, coalescing granulomas are evenly placed (H&E, ×40). (B) Granulomas of epithelioid cells with a multinucleated giant cell, peripheral lymphoid cells and collagen bundles are noted (H&E, ×200).

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