Clin Psychopharmacol Neurosci.  2016 May;14(2):221-225. 10.9758/cpn.2016.14.2.221.

Acute Dystonia Following a Switch in Treatment from Atomoxetine to Low-dose Aripiprazole

• BaÅŸay O
• Basay BK
• Öztürk O
• Yüncü Z

• KMID: 2170993
• DOI: http://doi.org/10.9758/cpn.2016.14.2.221

Abstract

The present report describes the cases of a 17-year-old male patient and a 13-year-old female patient who developed acute dystonia following the administration of low-dose aripiprazole (5 mg/day) after the cessation of atomoxetine treatment. Although aripiprazole-induced dystonia has been previously reported in the literature, it is rare, and most of these cases were associated with doses higher than 5 mg/day. Furthermore, both of the patients in the present study discontinued atomoxetine prior to the initiation of aripiprazole treatment; thus, this report also discussed the possible mechanisms underlying the manifestation of dystonia from the perspective of neurotransmitter activity.

Keyword

Aripiprazole; Atomoxetine; Dystonia

MeSH Terms

Adolescent
Dystonia*
Female
Humans
Male
Neurotransmitter Agents
Neurotransmitter Agents