Ewha Med J.  1990 Dec;13(4):347-354. 10.12771/emj.1990.13.4.347.

A Comparative Study between Surgery Alone and Surgery with Postoperative Administration of Antitubeculos Chemotherapeutics for Regional Complications Following BCG Vaccination

• Choi KJ

• KMID: 2170849
• DOI: http://doi.org/10.12771/emj.1990.13.4.347

Abstract

Author described 57 pediatric surgical patients who were undergoing Surgery for regional complications following BCG vaccination at Ewha Womans University Hospital. The patients were randomly allocated either to surgery alone or surgery with postoperative administation of antituberculous chemother apeutics. The result of this trial indicate the followings : 1) Among the total 57 cases, 31 cases were included into the surgery alone group(control group) and 26 cases were administration group of antituberculous chemotherapeutics following surgery(theeapy group). There was no statistically significant difference between both groups on several factors that may affect the curing process. 2) Postoperative complication rate was 1.8 percent and recurrence rate during follow-up after treatment completion is 6.5 percent. But there was no significant difference between both groups on complication rate and recurrence rate. 3) Postoperative treatment duration was less than 8 days in control group add was about 6.8 months in therapy group, and so postoperative therapy with antituberculous drugs did prolong the length of treatment period significantly(p<0.001). This results suggest that the postoperative administration of antituberculous chemotherapeutics for regional complications following BCG vaccination would rather have economic burden and inconvenience than any benefical effect.

MeSH Terms

Female
Follow-Up Studies
Humans
Mycobacterium bovis*
Postoperative Complications
Recurrence
Vaccination*