Infect Chemother.  2008 Aug;40(4):191-198. 10.3947/ic.2008.40.4.191.

Status of Vivax Malaria after Re-emergence in South Korea

Affiliations
  • 1Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Korea.
  • 2Department of Microbiology, Graduate School of Medicine, Gachon University of Medicine and Science, Korea. seorak@dreamwiz.com

Abstract

Vivax malaria re-emerged in the Republic of Korea (ROK) in 1993. Sixteen years have passed and epidemiological characteristics have changed since then. The annual incidence of this disease which had increased rapidly through 2000, started to decrease rapidly in 2001, reaching about 800 cases in 2004. But it started to change again in 2005 and since then, about 2000 cases are occurring annually. Not only the cases are increasing but also geographic distributions are expanding into cities and counties bordering Seoul. Based on these data, possibility of occurrence of local transmission is very high. Malaria situation in North Korea is not so different from the ROK. Although annual incidence of diseases are decreasing every year, incidences in areas near demilitarized zone which can affect the ROK are still serious. And now economical and cultural exchange between the ROK and Nouth Korea is increasing every year. This also means that risks of exposure to this disease among civilians are also increasing. Control strategies in the beginning of resurgence had been focused mainly on decreasing transmission and cases of malaria. Main parts of these strategies were vector control and chloroquine chemoprophylaxis among soldiers stationed in high-risk areas. But now, epidemiological characteristics have changed and our control strategies need adjustment considering these changes.

Keyword

Malaria; Plasmodium vivax; Republic of Korea; Epidemiology

MeSH Terms

Chemoprevention
Chloroquine
Democratic People's Republic of Korea
Humans
Incidence
Korea
Malaria
Malaria, Vivax
Military Personnel
Plasmodium vivax
Republic of Korea
Chloroquine

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Clinical Characteristics of Vivax Malaria and Analysis of Recurred Patients
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Reference

1. Sinden R, Gilles H. Warrell DA, Gilles HM, editors. The malaria parasites. Essential malariology. 2002. 4th ed. London: Arnold;8.
2. Singh B. . Plasmodium knowlesi: a zoonosis of public health importance. Current Topics in Malaria. 2008. Singapore: 4A.
3. Sachs J, Malaney P. The economic and social burden of malaria. Nature. 2002. 415:680–685.
Article
4. Gilles HM. Gilles HM, Warrell DA, editors. The malaria parasites. Bruce-Chwatt's Essential malariology. 1993. 3rd ed. London: Arnold;12.
5. Shute PG, Lupascu G, Branzei P, Maryon M, Constantinescu P, Bruce-Chwatt LJ, Draper CC, Killick-Kendrick R, Garnham PC. A strain of Plasmodium vivax characterized by predominantly prolonged incubation: the effect of numbers of sporozoites on the length of the prepatent period. Trans R Soc Trop Med Hyg. 1977. 70:474–481.
Article
6. Hasegawa Y. Malaria in Korea. J Chosen Med Soc. 1913. 4:53–69.
7. Himeno K. On the malaria endemicity in Kangnung area in Kangwon-do. Mansen No Ikai. 1926. 62:59–66.
8. Kobayashi H. Review on malaria and Anopheles in Korea. J Chosen Med Soc. 1932. 22:107–111.
9. Hale T, Halpenny GW. Malaria in Korean veterans. Can Med Assoc J. 1953. 68:444–448.
10. Hankey DD, Jones R Jr, Coatney GR, Alving AS, Coker WG, Garrison PL, Donovan WN. Korean vivax malaria I. Natural history and response to chloroquine. Am J Trop Med Hyg. 1953. 2:958–969.
11. Alving AS, Hankey DD, Coatney GR, Jones R Jr, Coker WG, Garrison PL, Donovan WN. Korean vivax malaria II. Curative treatment with pamaquine and primaquine. Am J Trop Med Hyg. 1953. 2:970–976.
12. Coatney GR, Alving AS, Jones R Jr, Hankey DD, Robinson DH, Garrison PL, Coker WG, Donovan WN, Lorenzo AD, Marx RL, Simmons IH. Korean vivax malaria V. cure of the infection by primaquine administered during long-term latency. Am J Trop Med Hyg. 1953. 2:985–988.
13. Jones R Jr, Jackson LS, Di Lorenzo A, Marx RL, Levy BL, Kenny EC, Gilbert M, Johnston MN, Alving AS. Korean vivax malaria III. Curative effect and toxicity of primaquine in doses from 10 to 30 mg. daily. Am J Trop Med Hyg. 1953. 2:977–982.
14. Lee SW, Shim JC, Kang YB, Ree HI. Investigation of Malaria Prevalence in Daesin-myon, Yoju-gun, and Kaegun-myon, Yang-pyong-gun, Kyonggi-do Province. Rep Natl Ins Health. 1972. 9:135–140.
15. Paik YH, Ree HI, Shim JC. Malaria in Korea. Jpn J Exp Med. 1988. 58:55–66.
17. Paik YH, Tsai FC. A note on the epidemiology of Korean vivax malaria. New Med. 1963. 6:37–44.
18. Park JW, Klein TA, Lee HC, Pacha LA, Ryu SH, Yeom JS, Moon SH, Kim TS, Chai JY, Oh MD, Choe KW. Vivax malaria: a continuing health threat to the Republic of Korea. Am J Trop Med Hyg. 2003. 69:159–167.
Article
19. Yeom JS, Ryu SH, Oh S, Lee WJ, Kim TS, Kim KH, Kim YA, Ahn SY, Cha JE, Park JW. Status of Plasmodium vivax malaria in the Republic of Korea during 2001-2003. Am J Trop Med Hyg. 2005. 73:604–608.
Article
20. Yeom JS, Kim TS, Oh S, Sim JB, Barn JS, Kim HJ, Kim YA, Ahn SY, Shin MY, Yoo JA, Park JW. Plasmodium vivax malaria in the Republic of Korea during 2004-2005: changing patterns of infection. Am J Trop Med Hyg. 2007. 76:865–868.
Article
21. Yeom JS, Ryu SH, Oh S, Choi DH, Song KJ, Oh YH, Lee JH, Kim YA, Ahn SY, Yang HY, Cha JE, Park JW. Evaluation of anti-malarial effects of mass chemoprophylaxis in the Republic of Korea army. J Korean Med Sci. 2005. 20:707–712.
Article
24. WHO regional office for South East Asia. Trend of malaria cases (including clinical) in DPRK, 2002-2005. Available from URL: http://www.searo.who.int/LinkFiles/Malaria_in_the_SEAR_trend.pdf.
26. WHO regional office for South East Asia. Level of malaria endemicity in DPRK. Available from:URL: http://www.searo.who.int/LinkFiles/Malaria_in_the_SEAR_trend.pdf.
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