J Bacteriol Virol.  2016 Mar;46(1):36-43. 10.4167/jbv.2016.46.1.36.

Reduction Effect of Royal Jelly and Rape Honey Alone and in Combination Against Methicillin-Resistant Staphylococcus aureus (MRSA) Strains

Affiliations
  • 1Department of Food Hygiene and Control, Veterinary Legislation and Management, Trakia University, Faculty of Veterinary Medicine, 6000 Stara Zagora, Bulgaria. dinkodinkov@abv.bg
  • 2Department of Special Branches - Bees, Institute of Animal Science, Kostinbrod, Bulgaria.
  • 3School of Veterinary Medicine, Aristotle University of Thessaloniki, Greece.

Abstract

Multidrug resistant and methicilin-resistant Staphylococcus aureus (MRSA) is involved in severe difficult to treat skin and soft tissue infections in humans. In the present study the antibacterial reduction effect of royal jelly (RJ), rape honey (RH), as well as in combination (RJ:RH, 1:100 w/w) against multidrug resistant MRSA strains was evaluated by means of a microbiological method "in vitro". Royal jelly and rape honey mixture possessed a higher antibacterial activity than rape honey. The concentrations of royal jelly (20 and 30% v/v) had a total inhibitory effect against tested MRSA strains. Royal jelly alone and in rape honey mix (RJ:RH, 1:100 w/w) have a potential as alternative therapeutics against MRSA strains, resistant for antibiotics.

Keyword

Bee honey; Royal jelly; Antibacterial activity; Methicilin-resistant Staphylococcus aureus

MeSH Terms

Anti-Bacterial Agents
Honey*
Humans
Methicillin Resistance*
Methicillin-Resistant Staphylococcus aureus*
Rape*
Skin
Soft Tissue Infections
Staphylococcus aureus
Anti-Bacterial Agents

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