Allergy Asthma Immunol Res.  2015 Jul;7(4):416-417. 10.4168/aair.2015.7.4.416.

Basophil Activation Tests: A Diagnostic Break-Through in Opiate Allergy

  • 1Faculty of Medicine and Health Science, Department of Immunology-Allergology-Rheumatology, University of Antwerp, Antwerp University Hospital, Antwerpen, Belgium.


No abstract available.

MeSH Terms



  • Figure Representative plot CD63 appearance and histamine release in response to buffer, anti-IgE as a positive control, pholcodine 10 µg/mL (top), and the structurally almost similar opiates codeine 100 mg/mL and morphine 100 µg/mL (both bottom) (From9: with permission). Intracellular histamine and its release is analyzed flow cytometrically by an enzyme affinity method using the histaminase diamine oxidase (DAO) conjugated to laser-excitable fluorochromes.10


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