Clin Exp Otorhinolaryngol.  2011 Mar;4(1):44-48.

Larynx-Preserving Partial Pharyngectomy via Lateral Pharyngotomy for the Treatment of Small (T1~2) Hypopharyngeal Squamous Cell Carcinoma

• Lim YC
• Jeong HM
• Shin HA
• Choi EC

Abstract

OBJECTIVES
To evaluate the oncologic and functional results of larynx-preserving partial pharyngectomy (LPP) via lateral pharyngotomy approach as a primary treatment for small (T1 or T2) hypopharyngeal squamous cell carcinoma (HPSCC).
METHODS
We performed a retrospective review of 23 patients who underwent LPP through lateral pharyngotomy approach for small HPSCC at the our department between January 1991 and June 2007. Fourteen (61%) patients had adjuvant postoperative radiotherapy.
RESULTS
The 2-years and 5-years disease specific survival rate was 77% and 61%, respectively. Nine patients (39%) had tumor recurrence. The most common pattern of recurrence was isolated distant failure (n=4, 44%) followed by local (n=2, 22%) and loco-regional (n=3, 34%) recurrence. The ultimate cure rate of the primary tumor was 87% (20 of 23). Twenty-two of the 23 patients (95%) could be decannulated, tolerate an oral diet, and had acceptable postoperative phonatory function.
CONCLUSION
LPP via lateral pharyngotomy approach appears to be a feasible procedure for selected small HPSCC patients in terms of both oncologic and functional outcomes.

Keyword

Hypopharyngeal neoplasm; Pharyngectomy; Lateral pharyngotomy; Adjuvant radiotherapy

MeSH Terms

Carcinoma, Squamous Cell
Diet
Humans
Hypopharyngeal Neoplasms
Pharyngectomy
Radiotherapy, Adjuvant
Recurrence
Retrospective Studies
Survival Rate

Figure

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  Fig. 1 Five-years survival rate of all patients.

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