Cancer Res Treat.  2001 Jun;33(3):269-273.

A Case of Primary MALT Lymphoma of the Breast

• Jung SW
• Kim BS
• Park JH
• Kim SK
• Seo HE
• Shin DK
• Lee JL
• Kim IS
• Lee DS
• Kim DS

Abstract

Primary malignant lymphoma of the breast is rare. The incidence of primary malignant lymphomas of the breast is 0.04% to 0.5% of all malignant tumors of the breast and 0.07% of all non-Hodgkin's lymphomas, and comprises 1.7% of extranodal malignant lymphomas that occur in Western countries. The incidence of mucosa- associated lymphoid tissue (MALT) lymphoma of the breast is reported to be between 0% and 75% of all primary malignant breast lymphomas in United States and Japan, but the incidence in Korea is unknown. MALT is characterized by indolent behavior and good has a prognosis. The authors report on a patient who has a primary MALT lymphoma of the breast. She was treated by surgical excision, which was followed by radiation therapy. Histologically, her lymphoma type transformed into a diffuse large B-cell tumor after 10months. She received combination chemotherapy and achieved a complete state of remission. She then underwent autologous peripheral blood stem cell transplantation along with high dose chemotherapy. To our knowledge, this is the first case report in the literature in Korea.

Keyword

Breast; MALT lymphoma

MeSH Terms

B-Lymphocytes
Breast*
Drug Therapy
Drug Therapy, Combination
Humans
Incidence
Japan
Korea
Lymphoid Tissue
Lymphoma
Lymphoma, B-Cell, Marginal Zone*
Lymphoma, Non-Hodgkin
Peripheral Blood Stem Cell Transplantation
Prognosis
United States