Brain Tumor Res Treat.  2016 Apr;4(1):13-16. 10.14791/btrt.2016.4.1.13.

Recurrent Giant Cell Tumor of Skull Combined with Multiple Aneurysms

Affiliations
  • 1Department of Neurosurgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. YEDAMIN@yuhs.ac

Abstract

Giant cell tumors are benign but locally invasive and frequently recur. Giant cell tumors of the skull are extremely rare. A patient underwent a surgery to remove a tumor, but the tumor recurred. Additionally, the patient developed multiple aneurysms. The patient underwent total tumor resection and trapping for the aneurysms, followed by radiotherapy. We report this rare case and suggest some possibilities for treating tumor growth combined with aneurysm development.

Keyword

Giant cell tumor; Cerebral aneurysm; Temporal bone; Recurrence

MeSH Terms

Aneurysm*
Giant Cell Tumors*
Giant Cells*
Humans
Intracranial Aneurysm
Radiotherapy
Recurrence
Skull*
Temporal Bone

Figure

  • Fig. 1 Comparison of MR images before and after first operation. A: Pre-operative MRI shows a tumor located at left cerebellopontine angle. B: After the first surgery, the tumor was removed.

  • Fig. 2 A: Recurred tumor identified on MRI 9 months after initial surgery. B: Beaded-pattern aneurysms on cerebral angiography. C: The tumor was removed totally after the second surgery.

  • Fig. 3 A: Pathologic specimen collected from the second surgery (hematoxylin and eosin, ×200). B: Dural invasions by tumor cells are noted.


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