J Korean Soc Radiol.  2016 May;74(5):299-307. 10.3348/jksr.2016.74.5.299.

CT Quantification of Central Airway in Tracheobronchomalacia

Affiliations
  • 1Department of Radiology, Chonbuk National University Hospital, Jeonju, Korea. gyjin@jbnu.ac.kr
  • 2Department of Radiology, Chonbuk National University School of Medicine, Jeonju, Korea.
  • 3Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.

Abstract

PURPOSE
To know which factors help to diagnose tracheobronchomalacia (TBM) using CT quantification of central airway.
MATERIALS AND METHODS
From April 2013 to July 2014, 19 patients (68.0 ± 15.0 years; 6 male, 13 female) were diagnosed as TBM on CT. As case-matching, 38 normal subjects (65.5 ± 21.5 years; 6 male, 13 female) were selected. All 57 subjects underwent CT with end-inspiration and end-expiration. Airway parameters of trachea and both main bronchus were assessed using software (VIDA diagnostic). Airway parameters of TBM patients and normal subjects were compared using the Student t-test.
RESULTS
In expiration, both wall perimeter and wall thickness in TBM patients were significantly smaller than normal subjects (wall perimeter: trachea, 43.97 mm vs. 49.04 mm, p = 0.020; right main bronchus, 33.52 mm vs. 42.69 mm, p < 0.001; left main bronchus, 26.76 mm vs. 31.88 mm, p = 0.012; wall thickness: trachea, 1.89 mm vs. 2.22 mm, p = 0.017; right main bronchus, 1.64 mm vs. 1.83 mm, p = 0.021; left main bronchus, 1.61 mm vs. 1.75 mm, p = 0.016).
CONCLUSION
Wall thinning and decreased perimeter of central airway of expiration by CT quantification would be a new diagnostic indicators in TBM.


MeSH Terms

Airway Remodeling
Bronchi
Evaluation Studies as Topic
Humans
Male
Trachea
Tracheobronchomalacia*
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