Ann Dermatol.  2016 Jun;28(3):398-399. 10.5021/ad.2016.28.3.398.

A Case of Multiple Canaliform Median Raphe Cysts Showing a Mixed Type Lining of Epithelium: A Case Report and Review of the Literature

Affiliations
  • 1Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. dykim@yuhs.ac
  • 2Drs. Woo and Hann's Skin Center, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Epithelium*

Figure

  • Fig. 1 Linearly arranged, multiple, whitish cysts along the perineal raphe. The arrow indicates the canalicular appearance of the cysts. The arrowhead indicates the biopsy site.

  • Fig. 2 (A) The biopsy revealed cysts located in the dermis that showed variable lining (H&E, ×100). (B) Focal part of the cyst wall lined by stratified squamous epithelium with well-formed granular layer and keratin flakes (H&E, ×400). (C) Focal part of the cyst wall lined by cuboidal urothelium-like epithelium with mucinous cells (H&E, ×400). The arrows indicate the mucinous cells.


Reference

1. Shao IH, Chen TD, Shao HT, Chen HW. Male median raphe cysts: serial retrospective analysis and histopathological classification. Diagn Pathol. 2012; 7:121.
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2. Nagore E, Sánchez-Motilla JM, Febrer MI, Aliaga A. Median raphe cysts of the penis: a report of five cases. Pediatr Dermatol. 1998; 15:191–193.
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3. Dini M, Baroni G, Colafranceschi M. Median raphe cyst of the penis: a report of two cases with immunohistochemical investigation. Am J Dermatopathol. 2001; 23:320–324.
4. Shiraki IW. Parametal cysts of the glans penis: a report of 9 cases. J Urol. 1975; 114:544–548.
5. Verma SB. Canal-like median raphe cysts: an unusual presentation of an unusual condition. Clin Exp Dermatol. 2009; 34:e857–e858.
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