Ann Dermatol.  2016 Jun;28(3):388-390. 10.5021/ad.2016.28.3.388.

Classic Juvenile Pityriasis Rubra Pilaris Treated with Oral Alitretinoin

• Lee HS
• Lee ES

• KMID: 2164651
• DOI: http://doi.org/10.5021/ad.2016.28.3.388

Abstract

No abstract available.

MeSH Terms

Pityriasis Rubra Pilaris*
Pityriasis*

Figure

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  Fig. 1 Clinical findings of pityriasis rubra pilaris presented at the first visit to our hospital. Multiple erythematous scaly papuloplaques on (A) the trunk and (B) the lower extremities. (C) Histopathologic findings revealed regular acanthosis with broad rete ridge, parakeratosis, and perivascular lymphocytic infiltration with occasional eosinophils (H&E; C: ×100, inset: ×200).

• 

  Fig. 2 No skin lesion was seen on the (A) trunk and (B) lower extremities after the 5 months course of oral alitretinoin.

Reference

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2. Molin S, Ruzicka T. Treatment of refractory pityriasis rubra pilaris with oral alitretinoin: case report. Br J Dermatol. 2010; 163:221–223.

3. Amann PM, Susic M, Glüder F, Berger H, Krapf W, Löffler H. Alitretinoin (9-cis retinoic acid) is effective against pityriasis rubra pilaris: a retrospective clinical study. Acta Derm Venereol. 2015; 95:329–331.

4. Pampín A, Gómez-de la Fuente E, Caro Gutiérrez MD, López-Estebaranz JL. Successful treatment of atypical adult pityriasis rubra pilaris with oral alitretinoin. J Am Acad Dermatol. 2013; 69:e105–e106.

5. Schmitt L, Inhoff O, Dippel E. Oral alitretinoin for the treatment of recalcitrant pityriasis rubra pilaris. Case Rep Dermatol. 2011; 3:85–88.