Child Kidney Dis.  2016 Apr;20(1):33-36. 10.3339/jkspn.2016.20.1.33.

Pathogenetic Overlapping of Renovascular Hypertension Developed in a Child with Takayasu Arteritis: 'One-clip, One and Half-kidney Model'

• Lee SJ
• Baek HS
• Jang HM
• Kim HK
• Huh S
• Cho MH

• KMID: 2163322
• DOI: http://doi.org/10.3339/jkspn.2016.20.1.33

Abstract

There are two pathogenic models of renovascular hypertension (RVH) originating from renal artery stenosis. We noted a case of a boy who had severe hypertension with atrophic left kidney, hypertrophic right kidney, a segmental stricture of the abdominal aorta, and total occlusion of the right renal artery. Due to the atrophic change of the contralateral, unclipped left kidney, this patient presented with various clinical manifestations related to both models of pathogenesis of RVH occurring at the same time. We conclude that this patient presented with the middle stage of the two RVH pathogenetic models, so called the 'one-clip, one and half-kidney model.'

Keyword

Pathogenesis; Renovascular hypertension; Takayasu arteritis; Renin-angiotensin system

MeSH Terms

Aorta, Abdominal
Child*
Constriction, Pathologic
Humans
Hypertension
Hypertension, Renovascular*
Kidney
Male
Renal Artery
Renal Artery Obstruction
Renin-Angiotensin System
Takayasu Arteritis*