Pediatr Infect Vaccine.  2016 Apr;23(1):40-45. 10.14776/piv.2016.23.1.40.

Etiology of Acute Pharyngotonsillitis in Children: The Presence of Viruses and Bacteria

• Pyeon JS
• Moon KP
• Kang JH
• Ma SH
• Bae SM

• KMID: 2163222
• DOI: http://doi.org/10.14776/piv.2016.23.1.40

Abstract

PURPOSE
The purpose of this study was to investigate the etiology of acute pharygotonsillitis in pediatric patients.
METHODS
Pharyngeal swabs from patients with acute pharyngotonsillitis were evaluated for viruses and bacterial organisms from March 2010 through March 2011.
RESULTS
Of 615 patients, potentially pathogenic bacteria were isolated in 40 (6.5%), viruses were isolated in 310 (50.4%), and no pathogens were isolated in 267 patients (43.4%). Both viral and bacterial pathogens were found in 2 (0.3%). Of 40 patients with bacterial pathogens, group A streptococci were found in 31 (77.5%). Among 310 patients with virus infection, adenovirus was the most frequently recovered (203 patients; 65.5%), followed by rhinovirus (65 patients; 21.0%), enterovirus (43 patients; 13.9%) and coronavirus (18 patients; 5.8%). There were 25 patients who had been coinfected with 2 viruses. In viral pharyngotonsillitis, cough, rhinorrhea, conjunctivitis and diarrhea were prominent. On the other hand, pharyngeal injection and pharyngeal petechiae were prominent in bacterial pharyngotonsillitis.
CONCLUSIONS
Virus infection was a big part of acute pharyngotonsillitis and there were differences in clinical manifestations among viral and bacterial infections. Therefore, we need to distinguish between virus infection and bacterial infection using clinical signs for preventing the abuse of antibiotics.

Keyword

Acute pharyngotonsillitis; Children; Etiology

MeSH Terms

Adenoviridae Infections
Anti-Bacterial Agents
Bacteria*
Bacterial Infections
Child*
Conjunctivitis
Coronavirus
Cough
Diarrhea
Enterovirus
Hand
Humans
Purpura
Rhinovirus
Anti-Bacterial Agents

Figure

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  Fig. 1. Microbial findings with aucte pharyngotonsillitis according to patient's age groups, March 2010 to March 2011 (N=615).

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  Fig. 2. Monthly distribution of Group A streptococcus, adenovirus, coronavirus, rhinovirus and enterovirus in pediatric patients with acute pharyngotonsillitis, March 2010-March 2011.

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  Fig. 3. Symptoms and physical findings in pediatric patients with acute pharyngotonsillitis, according to microbial agents (bacteria or virus).

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