J Korean Orthop Assoc.  2016 Apr;51(2):139-144. 10.4055/jkoa.2016.51.2.139.

Quality of Life in Patients with Osteochondromatosis

  • 1Department of Orthopedic Surgery, Kyungpook National University School of Medicine, Daegu, Korea.
  • 2Department of Preventive Medicine, Kyungpook National University School of Medicine, Daegu, Korea. kusmac25@knu.ac.kr
  • 3Department of Physiology, Kyungpook National University School of Medicine, Daegu, Korea.


The purpose of this study is to help predict the prognosis of multiple osteochondromatosis patients with the investigation of social function, pain, physical function and quality of life of patients.
Forty-five cases were diagnosed as multiple osteochondromatosis from March 1993 to June 2014. We performed a survey on pain, daily life, school or work life assessment of research and development-36. Forty-five people who responded to the survey completely were enrolled. Variable factors, including physical functioning, role limitations due to physical health, role limitations due to emotional problems, energy/fatigue, emotional well-being, social functioning, pain, and general health state were considered as elements related to quality of life. In addition, we investigated significant factors for multiple osteochondromatosis patients, and analyzed the survey by scoring. Related factors included age (over 18 years and under 18 years), gender, body mass index, operation, joint deformity, recurrence of disease, family history, the number of involved joints and the location of tumor. Statistical analyses were performed using SAS ver. 9.3 (SAS Inc., Cary, NC, USA). p-values of <0.05 were deemed statistically significant.
Patients with a family history of multiple osteochondromatosis showed a significantly decreased result of assessment, physical function, vitality of life, social activities, and health state. In addition, there was a tendency of a poor influence in pain, emotional wellbeing, and general health.
The results suggest that family history is a significant factor influencing and predicting the quality of life. In other words, the developed patients in the household including patients with severe enough for the rest of the family to know have poor prognosis. Through this study multiple osteochondromatosis is a chronic disease having a profound impact on quality of life.


multiple hereditary exostoses; quality of life; pain; family relations

MeSH Terms

Body Mass Index
Chronic Disease
Congenital Abnormalities
Exostoses, Multiple Hereditary
Family Characteristics
Family Relations
Quality of Life*
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