Ultrasonography.  2015 Apr;34(2):148-152. 10.14366/usg.14050.

Necrotic lymphoma in a patient with post-transplantation lymphoproliferative disorder: ultrasonography and CT findings with pathologic correlation

• Lee M
• Kim SK
• Chung YE
• Choi JY
• Park MS
• Lim JS
• Kim MJ
• Kim H

• KMID: 2159390
• DOI: http://doi.org/10.14366/usg.14050

Abstract

Seventeen months after kidney transplantation for the treatment of nephrotic syndrome, a retroperitoneal mass was incidentally detected in a 30-year-old man during routine follow-up. Ultrasonography revealed a mass measuring 5.5 cmx4.3 cm located between the liver and the atrophic right kidney, which showed markedly heterogeneous internal echogenicity. Contrast-enhanced computed tomography displayed a mild degree of enhancement only at the periphery of the mass, while the center lacked perceivable intensification. The patient underwent surgical resection. The final pathological diagnosis was non-Hodgkin lymphoma (diffuse large B-cell lymphoma), and extensive necrosis was observed on microscopic examination. We found that the prominent heterogeneous echogenicity of the mass (an unusual finding of lymphoma) demonstrated on ultrasonography is a result of extensive necrosis, which may sometimes occur in patients with post-transplantation lymphoproliferative disorder.

Keyword

Lymphoma; Ultrasonography; Immunocompromised host

MeSH Terms

Adult
B-Lymphocytes
Diagnosis
Follow-Up Studies
Humans
Immunocompromised Host
Kidney
Kidney Transplantation
Liver
Lymphoma*
Lymphoma, Non-Hodgkin
Lymphoproliferative Disorders*
Necrosis
Nephrotic Syndrome
Ultrasonography*