Korean J Helicobacter Up Gastrointest Res.  2016 Mar;16(1):46-51. 10.7704/kjhugr.2016.16.1.46.

Extensive Bone Metastasis following Curative Endoscopic Submucosal Dissection for Early Gastric Cancer: A Case Report

Affiliations
  • 1Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea. iliad@jnu.ac.kr, drwookyun@jnu.ac.kr
  • 2Department of Radiology, Chonnam National University Medical School, Gwangju, Korea.
  • 3Department of Pathology, Chonnam National University Medical School, Gwangju, Korea.

Abstract

The therapeutic indication for endoscopic submucosal dissection (ESD) can be expanded to treat small-sized (<2 cm) early gastric cancer (EGC) with undifferentiated histology. Here, we report the case of a 62-year-old woman in whom EGC was initially diagnosed by endoscopy and CT. She subsequently underwent ESD. Histological examination revealed a mixed type adenocarcinoma with poorly differentiated histology confined to the mucosa without ulcer and lymphovascular involvement. Subsequent regular examinations showed no recurrence for 7 years. She complained of fatigue and weight loss on the 7th year of follow-up. Radiologic examination showed multiple bone metastases and the bone biopsy specimen revealed adenocarcinoma resembling the previous EGC.

Keyword

Early gastric cancer; Endoscopic submucosal dissection; Bone metastasis

MeSH Terms

Adenocarcinoma
Biopsy
Endoscopy
Fatigue
Female
Follow-Up Studies
Humans
Middle Aged
Mucous Membrane
Neoplasm Metastasis*
Recurrence
Stomach Neoplasms*
Ulcer
Weight Loss
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