Ann Dermatol.  2002 Dec;14(4):210-212. 10.5021/ad.2002.14.4.210.

Ethylene Oxide(EO) Induced Cutaneous Hypersensitivity in a Patient on Hemodialysis

• Kim YJ
• Chang DS
• Kim MN
• Hong CK
• Ro BI

• KMID: 2158753
• DOI: http://doi.org/10.5021/ad.2002.14.4.210

Abstract

A 46-year-old male patient had recurrent episodes of generalized pruritic wheals during hemodialysis. He has experienced urticaria during hemodialysis whenever he used a capillary dialyser sterilized by ethylene oxide(EO, Polysulfone-) gas which is used to sterilize hemodialysers and other medical equipment. On the other hand, capillary dialyser sterilized by Gamma ray (Hemophad) has not evoked urticaria. Although the presence of EO-specific antibodies was not detected, urticarial rash never developed when the equipment was switched to a gamma-sterilized one. We herein report a case referred to ethylene oxide induced cutaneous hypersensitivity during hemodialysis.

Keyword

Hemodialysis; Ethylene oxide(EO); Hypersensitivity

MeSH Terms

Antibodies
Capillaries
Ethylene Oxide
Exanthema
Gamma Rays
Hand
Humans
Hypersensitivity*
Kidneys, Artificial
Male
Middle Aged
Renal Dialysis*
Urticaria
Antibodies
Ethylene Oxide