Ann Dermatol.  2015 Dec;27(6):793-794. 10.5021/ad.2015.27.6.793.

Cutaneous Metastasis of Choriocarcinoma

Affiliations
  • 1Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea. ahnsk@yonsei.ac.kr

Abstract

No abstract available.


MeSH Terms

Choriocarcinoma*
Female
Neoplasm Metastasis*
Pregnancy

Figure

  • Fig. 1 A solitary bean-sized oval reddish nodule on the vertex of the scalp.

  • Fig. 2 Marked red blood cell extravasation and dermal infiltration of anaplastic malignant tumor cells. Cytotrophoblastic cells (yellow arrow) with a polygonal clear cytoplasm and large vesicular nuclei with prominent nucleoli, and syncytiotrophoblastic cells (red arrow) with hyperchromatic nuclei and an eosinophillic cytoplasm are seen (H&E, ×200). Immunohistochemical staining of the cytoplasm of syncytiotrophoblasts against the human chorionic gonadotropin (hCG) antigen shows a strong positive reaction (inset; ×200).


Reference

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