Ann Dermatol.  2011 Sep;23(Suppl 1):S105-S107. 10.5021/ad.2011.23.S1.S105.

Acral Angioosteoma Cutis

• Lee EJ
• Lee JH
• Shin MK
• Lee SW
• Haw CR

• KMID: 2156764
• DOI: http://doi.org/10.5021/ad.2011.23.S1.S105

Abstract

Acral angioosteoma cutis is a rare disease first described in 2006 that is characterized by vascular proliferation with ossification at the acral area, and which bears clinical similarity to pyogenic granuloma. However, there is no lobular pattern in the capillary proliferation that is a typical histopathological feature in pyogenic granuloma. Metaplastic cutaneous ossification is associated with multiple skin diseases and inflammatory conditions such as scars, nevi, basal cell carcinomas, pilomatricomas, chondroid syringomas, and venous stasis. It is rarely associated with vascular proliferation diseases like hemangiomas and pyogenic granulomas. We report a case of capillary proliferation with ectopic bone formation in a 43-year-old female who presented with an ulcerative, dome-shaped subungual nodule on the left fourth toe, which appeared to be a pyogenic granuloma. Because the biopsy findings showed no lobular capillary proliferation, we determined that this case was consistent with acral angioosteoma cutis.

Keyword

Acral angioosteoma cutis; Pyogenic granuloma

MeSH Terms

Adenoma, Pleomorphic
Adult
Biopsy
Capillaries
Carcinoma, Basal Cell
Cicatrix
Female
Granuloma, Pyogenic
Hemangioma
Humans
Nevus
Osteogenesis
Pilomatrixoma
Rare Diseases
Skin Diseases
Toes
Ulcer
Ursidae

Figure

• 

  Fig. 1 0.5×0.5 cm mobile, ulcerated, erythematous dome shaped subungual papule on the patient;s left fourth toe. (A: front view, B: upper view).

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  Fig. 2 Results of histopathology analyses. (A) Dilated capillary network with poorly canalized vascular tufts and scattered basophilic bony trabeculeae (Hematoxylin and Eosin, ×100). (B) Three osteoblasts (arrow) lining osteoid and mineralized bony trabeculae with osteocytes within lacunae (Hematoxylin and Eosin, ×200). (C) Bony materials positively stained with von Kossa stain (×200).

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