Ann Dermatol.  2008 Sep;20(3):107-112. 10.5021/ad.2008.20.3.107.

Targeted Broadband UVB Phototherapy forthe Treatment of Localized Vitiligo

• Kim JE
• Ahn HH
• Kye YC

• KMID: 2156374
• DOI: http://doi.org/10.5021/ad.2008.20.3.107

Abstract

BACKGROUND: Several new treatments appear to have higher success rates than previous therapies for the treatment of vitiligo, and targeted phototherapy is an alternative that may prove to be time-efficient and an effective therapeutic option for the management of this condition.
OBJECTIVE
The aim of this study was to evaluate the efficacy of targeted broadband UVB phototherapy for the treatment of localized vitiligo.
METHODS
Fifty-three vitiliginous patches on thirty-five patients (16 males, 19 females) were treated using a targeted broadband UVB phototherapy device. Treatment was started at 70% of the minimal erythema dose, and then gradually increased. Lesions were treated twice a week for a maximum of 60 treatment sessions.
RESULTS
Subjects tolerated treatment well. Forty-one of the fifty-three patches (77.4%) achieved repigmentation on > or =75% of the treated areas. Best results were obtained on the face and neck; 20 of the 24 patches (83.3%) concerned achieved > or =75% repigmentation. The least response was on the hands and feet; 3 of 6 patches (50%) showed > or =75% repigmentation. The results were better for focal type than segmental type vitiligo.
CONCLUSION
Targeted broadband UVB phototherapy appears to be highly effective at restoring pigmentation in patients with localized vitiligo.

Keyword

Targeted broadband UVB phototherapy; Vitiligo

MeSH Terms

Erythema
Hand
Humans
Male
Phototherapy
Pigmentation
Vitiligo

Figure

• 

  Fig. 1 Vitiliginous patch on the right periocular area in a 12-year-old boy. (A) Before treatment, (B) After 26 treatment sessions.

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