Tuberc Respir Dis.  1994 Dec;41(6):597-603. 10.4046/trd.1994.41.6.597.

The Role of HRCT in the Follow-Up Evaluation of Diffuse Interstitial Pulmonary Fibrosis

• Kim HK
• Kwak SM
• Song KS
• Lim CM
• Koh YS
• Kim WS
• Kim DS
• Kim WD

• KMID: 2152151
• DOI: http://doi.org/10.4046/trd.1994.41.6.597

Abstract

BACKGROUND
Because of the power of HRCT to detect the minute changes in lung parenchyme and the advantage of noninvasiveness, it may be the ideal method of follow-up evaluation of the patients with diffuse interstitial pulmonary fibrosis. So the aim of the study is to find out whether the change of HRCT during the course of the disease can represent the change in symptom and pulmonary function rest.
METHODS
Thirteen patients with diagnosis of diffuse interstitial pulmonary fibrosis who had more than two times of HRCT during the course of disease were studied. The extent of the disease in HRCT was measured at three levels using image analyzer The ralationship between the percent change in the disease extent in HRCT, symptom score, and pulmonary function testis were analysed.
RESULTS
The change of disease extent in HRCT has good correlation with the change in dyspnea and diffusion capacity(r=0.716, p=0.0012). But there was no correlation between the change of HRCT and FVC or TLC. Also significant inverse correlation was noted between the change in dyspnea and diffusion capacity(r=-0.707, p=0.0047).
CONCLUSION
These data suggest that HRCT may be a good method of follow-up in diffuse interstitial pulmonary fibrosis.

Keyword

Diffuse interstitial pulmonary fibrosis; HRCT

MeSH Terms

Diagnosis
Diffusion
Dyspnea
Follow-Up Studies*
Humans
Lung
Pulmonary Fibrosis*
Testis