Korean J Dermatol.
2002 Jan;40(1):79-80.
A Case of Nail Changes Secondary to Docetaxel
- Affiliations
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- 1Department of Dermatology, College of Medicine, Korea University Korea. kumcihk@unitel.co.kr
- 2Department of Internal Medicine, College of Medicine, Korea University Korea.
Abstract
- Docetaxel is a new taxoid antineoplastic drug widely used for advanced breast cancer , ovarian cancer . Skin and nail toxicity are one of the more frequent nonhematologic adverse reactions. Especially, nail changes include dark pigmentation, subungual hemorrahage, acute paronychia, onycholysis, Beau s line etc. We have observed a striking example of multiple Beau s lines from all fingernails and toenails in a man receiving a docetaxel infusion for treatment of metastatic cancer with unknown-origin.
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