Korean Circ J.  1986 Mar;16(1):27-36. 10.4070/kcj.1986.16.1.27.

Comparative Study on Stress Electrocardiography and Thallium-201 Stress Myocardial Scintigraphic Imaging in Coronary Artery Disease

• Chung N
• Cho SY
• Jang YS
• Park KS
• Shim WH
• Lee WK

• KMID: 2145746
• DOI: http://doi.org/10.4070/kcj.1986.16.1.27

Abstract

To evaluate the diagnostic value of thallium-201 stress myocardial scintigraphic imaging and stress electrocardiography, sensitity, specificity and predicitive value of thallium-201 stress myocardial scintigraphic imaging were compared to simultaneously recorded 12 lead electrocardiography in 17 normal subjects and 30 patients with coronary artery disease who proved by coronary arteriography. The following results were obtained. 1) The mean age was 49.5+/-10.7 years(mean+/-SD)in subjects with normal coronary arteries and 53.1+/-8.8 years in patients with stenotic coronary arteries. 2) Fourteen patients had one-vessel disease, 10 two-vessel disease and 6 three-vessel disease. 3) Sensitivity of thallium myocardial scintigraphic imaging was higher than that of stress electrocardiography(86.7% vs 76.7%). 4) Specificity of both tests was same(70.6% vs 70.6%). 5) Sensitivity of thllium-201 stress myocardial scintigraphic imaging and stress electrocardigraphy in relation to the extent of coronary artery disease showed 78.6% vs 64.3% in one vessel disease, 90% vs 80% in two-vessel disease and 100% vs 100% in three-vessel disease. 6) Predictive value of thallium-201 stress myocardial scintigraphic imaging and stress electrocardiography revealed 83.9% vs 82% in the postive test and 75% vs 63.2% in the negative test. In conclusion, even though thallium-201 stress myocardial scintigraphic imaging was superior to stress electrocardiography in diagnosing coronary artery disease, scintigraphic defects were noted in 5 subjects with normal coronary arteries which could mislead to erroneous diagnosis of coronary artery disease. This point should be taken into consideration in the interpretation of thallium-201 stress myocardial scintigraphic imaging.

MeSH Terms

Angiography
Coronary Artery Disease*
Coronary Vessels*
Diagnosis
Electrocardiography*
Humans
Sensitivity and Specificity
Thallium
Thallium