J Korean Surg Soc.  2001 Feb;60(2):213-218.

Gallbladder Dysmotility and Gallstone Development after Gastrectomy in Gastric Cancer Patients

• Kwon YD
• Park KH
• Park KH
• Joo DH
• Lee HI
• Park SH
• Yu YW
• Chung DS
• Cheon BY

Abstract

PURPOSE: Gallstone disease has been presumed to be a sequellae of gastrectomy. To know correlation between gallbladder disease and gastrectomy, we check anatomical and functional status of gallbladder with ultrasonogram in our study.
METHODS
Gallbladder motility after gastrectomy was studied by means of measuring fasting and postprandial gallbladder volume using real time ultrasonography in 50 gastrectomized patients and in 28 controls (healthy but not operated gastric cancer patients) were selected as study subjects.
RESULTS
Mean fasting and postprandial gallbladder volume was significantly increased in gastrectomized patient group (FV: 37.63+/-20.70 ml, PV: 11.50+/-10.26 ml) than control group (FV: 22.17+/-10.35 ml, PV: 5.44+/-3.67 ml, p<0.01). The ejection fraction of gallbladder in gastrectomized patient group (69.05+/-14.57%)was significantly smaller than control group (75.57+/-10.26%, p<0.05).
CONCLUSION
The risk of gallbladder disease was independent of age, sex, and post-operative duration in our study. Gastrectomy may have the possibility of increasing the risk of gallbladder disease by causing gallbladder dysmotility and bile stasis. So, gallbladder motility evaluation would be helpful for prevention and understanding gallstone formation. Further study will be needed about the clinical benefits of prophylactic cholecystectomy during gastrectomy.

Keyword

Gastrectomy; Gall bladder stone; Gall bladder motility

MeSH Terms

Bile
Cholecystectomy
Fasting
Gallbladder Diseases
Gallbladder*
Gallstones*
Gastrectomy*
Humans
Stomach Neoplasms*
Ultrasonography