Korean J Med.  2001 Jul;61(1):77-81.

A case of primary solitary tuberculoma of the liver treated with antituberculosis chemotherapy and surgical excision

• Moon W
• Choi MS
• Lee JH
• Ryu MK
• Lee SS
• Kang WT
• Hong JR
• Bae MH
• Lee KS
• Paik SW
• Rhee JC
• Choi KW
• Cho JW
• Park CK

Abstract

The solitary form of primary hepatic tuberculosis is a rare disease. We report an unusual case of primary solitary hepatic tuberculosis treated with surgical resection and second-line antituberculosis chemotherapy due to the recurrence after first-line antituberculosis chemotherapy alone. A 36-year-old man was presented with right upper abdominal discomfort, chills and weight loss for 2 months. Computerized tomography demonstrated the solitary space occupying lesion on the left lobe of liver suggesting a malignant disease. The open biopsy revealed chronic granulomatous inflammation with multinucleated giant cells and caseous necrosis. The patient was treated with antituberculosis chemotherapy for nine months and eighteen months respectively with the interval of eighteen months. But the hepatic lesion had become larger and symptoms were aggravated after the discontinuation of therapy. He underwent surgical excision of the lesioin. With second-line antituberculosis chemotherapy, the symptoms improved in postoperative days. Twenty four months later, no evidence of recurrence was noted in symptoms, laboratory findings and imaging studies.

Keyword

Tuberculosis, hepatic

MeSH Terms

Adult
Biopsy
Chills
Drug Therapy*
Giant Cells
Humans
Inflammation
Liver*
Necrosis
Rare Diseases
Recurrence
Tuberculoma*
Tuberculosis, Hepatic
Weight Loss