Korean J Otolaryngol-Head Neck Surg.  1997 Oct;40(10):1476-1481.

Histiocytic Necrotizing Lymphadenitis(Kikuchi-Fujimoto Disease)-A Clinicopathologic Study of 4 Cases-

• Park CY
• Park HW
• Ban YS
• Kim KS

Abstract

Histiocytic necrotizing lymphadenitis(HNL), also known as Kikuchi-Fujimoto Disease(KFD) is a disease which mainly invades cervical lymph node without any particular reason. Lymphadenopathy can be unilaterally or bilaterally with mild pain and be accompanied with high fever, malaise and skin rashes. At times it shows hepatosplenomegaly, leukopenia and lymphatic cyst. These symptoms will be gone spontaneously without any specific treatments in several weeks or months, so the prognosis is comparatively satisfactory. It is confirmed only by excisional biopsy and must be differentiated from other diseases such as lymphoma, inflammatory and granulomatous lymphadenopathy, etc. Authors report the clinicopathologic findings of 4 cases of HNL with a review of literature.

Keyword

Histiocytic necrotizing lymphadenitis; Excisional biopsy

MeSH Terms

Biopsy
Exanthema
Fever
Histiocytic Necrotizing Lymphadenitis
Leukopenia
Lymph Nodes
Lymphatic Diseases
Lymphocele
Lymphoma
Prognosis