Korean J Otorhinolaryngol-Head Neck Surg.  2012 Sep;55(9):565-570. 10.3342/kjorl-hns.2012.55.9.565.

Comparative Study of Preoperative Imaging Detection and Localization Test for Hyperparathyroidism

Affiliations
  • 1Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University, Seoul, Korea. kytae@hanyang.ac.kr
  • 2Department of Nuclear Medicine, College of Medicine, Hanyang University, Seoul, Korea.
  • 3Department of Radiology, College of Medicine, Hanyang University, Seoul, Korea.

Abstract

BACKGROUND AND OBJECTIVES
Accurate preoperative localization of abnormal parathyroid gland is essential for successful parathyroidectomy. The aim of this study was to evaluate the accuracy of a localization test for hyperparathyroidism including ultrasonography (US), computed tomography (CT) and 99mTc-sestamibi scan.
SUBJECTS AND METHOD
We studied 47 patients with hyperparathyroidism who underwent parathyroidectomy from January 2003 through December 2010, retrospectively. 99mTc-sestamibi scan, US and CT were carried out as a preoperative localization test and their accuracy were analyzed according to the size, location and pathology of parathyroid lesions.
RESULTS
The accuracy of 99mTc-sestamibi scan, US and CT were 93%, 77% and 65%, respectively. The accuracy of 99mTc-sestamibi scan and CT combined was 94% and US and CT 73%. The accuracy of combination of US and 99mTc-sestamibi scan was 96%, which was not different depending on size, location and pathology of parathyroid lesions.
CONCLUSION
The combination of 99mTc-sestamibi scan and US is the most effective method for preoperative detection and the localization of hyperparathyroidism.

Keyword

Hyperparathyroidism; Localization; Parathyroidectomy; Ultrasonography; 99mTc-sestamibi scan

MeSH Terms

Humans
Hyperparathyroidism
Parathyroid Glands
Parathyroidectomy
Retrospective Studies
Technetium Tc 99m Sestamibi
Technetium Tc 99m Sestamibi
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