J Korean Neurol Assoc.  2004 Oct;22(5):539-544.

Two Cases of Wernicke Encephalopathy with Focal Cerebral Cortical Involvement and Convulsive Seizure

Affiliations
  • 1Department of Neurology, Catholic University of Daegu School of Medicine, Daegu, Korea. jekim2@cu.ac.kr

Abstract

We report two cases of Wernicke encephalopathy presenting with convulsive seizures. The first patient had been supplied with total parenteral nutrition due to acute pancreatitis and presented with partial seizure evolving to generalized seizure. The second patient had been malnourished due to alcoholism and recent dyspepsia after a gastrectomy, who presented with generalized seizure. Brain MRI revealed high-signal lesions in the focal cerebral cortex on T2-weighted, FLAIR, and diffusion-weighted images. After a thiamine injection, the patients recovered and abnormalities on the MRIs disappeared.

Keyword

Wernicke encephalopathy; Seizures; Cerebral cortex

MeSH Terms

Alcoholism
Brain
Cerebral Cortex
Dyspepsia
Gastrectomy
Humans
Magnetic Resonance Imaging
Pancreatitis
Parenteral Nutrition, Total
Seizures*
Thiamine
Wernicke Encephalopathy*
Thiamine
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