J Korean Neurol Assoc.  2011 May;29(2):133-135.

Pseudohypoparathyroidism Presented With Seizure

Affiliations
  • 1Department of Neurology, Eulji General Hospital, Eulji University, Seoul, Korea. jungju2@unitel.co.kr

Abstract

Pseudohypoparathyroidism (PHP) is a rare clinical syndrome characterized by hypocalcemia, hyperphosphatemia and increase of serum parathyroid hormone in association with unique clinical features. We recently experienced a typical PHP type Ia patient who presented with recurrent seizure and muscle spasms and electroencephalogram (EEG) showed generalized spike-and-wave discharges. With the correction of hypocalcemia, seizures did not recur and epileptiform discharges disappeared. We suggest that the possibility of PHP should be considered in patients with seizures showing hypocalcemia and hyperphosphatemia.

Keyword

Pseudohypoparathyroidism; Seizures; Electroencephalogram

MeSH Terms

Electroencephalography
Humans
Hyperphosphatemia
Hypocalcemia
Parathyroid Hormone
Pseudohypoparathyroidism
Seizures
Spasm
Parathyroid Hormone
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