J Korean Bone Joint Tumor Soc.
2011 Jun;17(1):17-22. 10.5292/jkbjts.2011.17.1.17.
Chondrosarcoma Arising from Benign Bone Tumor due to Malignant Transformation
- Affiliations
-
- 1Department of Orthopedic Surgery, Korea Cancer Center Hospital, Seoul, Korea. dgjeon@kcch.re.kr
- KMID: 2137039
- DOI: http://doi.org/10.5292/jkbjts.2011.17.1.17
Abstract
- PURPOSE
We analyzed the oncological outcome and prognostic factor of the chondrosarcoma arising from benign bone tumor due to malignant transformation.
MATERIALS AND METHODS
From April 1986 to April 2009, 18 cases were considered eligible. We analyzed retrospectively the patient's characteristics and prognostic factors that affect to the local recurrence and distant metastasis.
RESULTS
As classified by primary benign bone tumor, 4 cases were solitary osteochondroma, 11 cases were multiple osteochondromatosis and 3 cases were multiple enchondromatosis. The mean follow-up period was 85 months. The 5-year disease free survival rate of 18 patients was 85.9%. Their overall MSTS score was 25.2 (84%). There were local recurrence in 3 cases and no distant metastasis. We found that tumor location and surgical margin affected to the prognosis significantly.
CONCLUSION
In secondary chondrosarcoma patients, the prognosis was good relatively and tumor location and surgical margin are important prognosis factor.
