Tuberc Respir Dis.  2004 Feb;56(2):216-220. 10.4046/trd.2004.56.2.216.

Multiple Cavitary Pulmonary Metastases from Cholangiocarcinoma

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. sekyukim@yumc.yonsei.ac.kr
  • 2Department of Diagnostic Radiology, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
  • 4The Institute of Chest Diseases, Yonsei University College of Medicine, Seoul, Korea.
  • 5Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Korea.
  • 6Cancer Metastasis Research Center, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Because a cavitary pulmonary metastasis is rare, it may not be readily identified. However, various types of cancers can metastasize to the lung in the form of cavities. We report a case of a multiple cavitary metastases to the lung from a cholangiocarcinoma in a 60-year-old man. He complained of generalized weakness and a poor oral intake for 2 months. The plain chest radiography and the chest computed tomography showed multiple small thick-walled cavities and nodules the both lungs. A bronchoscopic examination revealed a focal irregularly elevated surface of the mucosa at the orifice of the superior segment of the right lower lobe and the biopsy demonstrated an infiltrative metastatic adenocarcinoma. The abdomen-pelvis computed tomography showed an ill-marginated and irregularly low-dense area in the right lobe of the liver and a diffuse dilatation of the peripheral intrahepatic bile ducts. The esophagogastroscopy and colonoscopy showed no abnormal findings. It was concluded that the cholangiocarcinoma of the liver metastasized to the lung in the form of cavities. Thereafter, the patient underwent six cycles of the systemic chemotherapy with gemcitabine and cisplatin, and the follow-up imaging studies showed a partial response.

Keyword

Cavity; Pulmonary Metastasis; Cholangiocarcinoma

MeSH Terms

Adenocarcinoma
Bile Ducts, Intrahepatic
Biopsy
Cholangiocarcinoma*
Cisplatin
Colonoscopy
Dilatation
Drug Therapy
Follow-Up Studies
Humans
Liver
Lung
Middle Aged
Mucous Membrane
Neoplasm Metastasis*
Radiography
Thorax
Cisplatin
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