J Korean Neurol Assoc.  2015 Nov;33(4):310-314. 10.17340/jkna.2015.4.11.

Balo's Concentric Sclerosis in a Patient with Previous Recurrent Optic Neuritis

• Kim JH
• Yoon JH
• Yum KS
• Yoon B
• Lee KO
• Kim YD
• Na SJ

• KMID: 2129320
• DOI: http://doi.org/10.17340/jkna.2015.4.11

Abstract

Balo's concentric sclerosis is regarded as a rare variant of multiple sclerosis. Traditionally, Balo's concentric sclerosis was a post-mortem diagnosis, but the recent introduction of brain magnetic resonance imaging (MRI) scans may allow noninvasive access without biopsy. Brain MRI findings of Balo's concentric sclerosis is characteristic concentric configuration of alternating bands of white matter of different pathology, with relatively preserved myelination alternating with regions of demyelination in the cerebral white matter. We report a case of Balo's concentric sclerosis with recurrent optic neuritis.

Keyword

Balo's concentric sclerosis; Multiple sclerosis

MeSH Terms

Biopsy
Brain
Demyelinating Diseases
Diagnosis
Diffuse Cerebral Sclerosis of Schilder*
Humans
Magnetic Resonance Imaging
Multiple Sclerosis
Myelin Sheath
Optic Neuritis*
Pathology