J Korean Ophthalmol Soc.  2003 Jul;44(7):1693-1699.

Amniotic Membrane Transplantation for Perforation and Impending Perforation of Cornea: Four Cases

• Kim HK
• Choi TH

Abstract

PURPOSE
To report successfully cured four cases of amniotic membrane transplantation(AMT) as a primary procedure in the cornea that was perforated or impending perforation. METHODS: We performed AMT on 1 case of corneal perforation due to chemical burn, 1 case of perforated descemetocele, 1 case of perforated corneal ulcer due to metallic foreign body and 1 case of impending corneal perforation due to recurrent keratitis. Three or four layers of amniotic membrane(AM) that preserved under -70degrees C were applied over the perforation site and anchored with 10-0 nylon interrupted or running sutures. In one case, a large AM piece was used as a temporary patch. After surgery, all cases were treated with systemic antibiotics, antibiotic eyedrops, and topical corticosteroids. RESULTS: Amniotic membrane transplantation was successful in sealing the perforation in all cases. All corneas remained stable and visual acuity improved. There was no infection or rejection postoperatively. CONCLUSIONS: Multilayer amniotic membrane transplantation allowed a successful repair of corneal perforations. This method may be a good alternative to patch graft or penetrating keratoplasty for treating corneal perforations.

Keyword

Amniotic membrane transplantation; Corneal perforation; Descemetocele

MeSH Terms

Adrenal Cortex Hormones
Amnion*
Anti-Bacterial Agents
Burns, Chemical
Cornea*
Corneal Perforation
Corneal Ulcer
Foreign Bodies
Keratitis
Keratoplasty, Penetrating
Nylons
Ophthalmic Solutions
Running
Sutures
Transplants
Visual Acuity
Adrenal Cortex Hormones
Anti-Bacterial Agents
Nylons
Ophthalmic Solutions