J Korean Ophthalmol Soc.
2003 Oct;44(10):2445-2450.
Bilateral Acute Retinal Necrosis Syndrome in the Patient with Acquired Immunodeficiency Syndrome
- Affiliations
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- 1Department of Ophthalmology, Seoul National University College of Medicine, Korea.
- 2Seoul Artificial Eye Center Seoul National University Hospital Clinical Research Institute, Korea. hgonyu@snu.ac.kr
Abstract
- PURPOSE
To report one case of bilateral acute retinal necrosis (ARN) syndrome in the patient with acquired immunodeficiency syndrome (AIDS). METHODS: Bilateral retinal necrosis, occlusive vasculitis, vitreous opacity and inflammatory reaction in anterior chamber were noted in a 48-years old man with AIDS. RESULTS: The patient was diagnosed as bilateral ARN, but did not respond to intravenous acyclovir therapy. However, the patient was successfully treated with intravenous ganciclovir at a dosage of 5 mg/kg/day, which resulted in resolution of retinal lesion and improvement of visual acuity without complications such as retinal detachment. CONCLUSIONS: CMV retinitis, progressive outer retinal necrosis, ocular syphilis should be considered in the differential diagnosis of ARN syndrome in the AIDS patients and alternative treatment with ganciclovir should be considered promptly when the patient do not respond to acyclovir therapy.
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