J Korean Ophthalmol Soc.  1996 May;37(5):913-920.

The Necessity of Topical Corticosteroid After Excimer Laser Photorefractive Keratectomy

• Lee JG
• Kim WJ
• Lee JH

Abstract

The effect of topical steroid application on clinical results of 215 eyes(126 patients) performed with excimer laser photorefractive keratectomy (PRK) from July 1993 to July 1994 was evaluated, postopertively. The range of myopia was between -2.5 and -11.5 diopter and followed for 9 months after PRK with Summit Omnimed(TM). Topical corticosteroid or non-steroidal antiinflammatory drug (NSAID) was not applied for one month after operation in all cases. After one month, in cases of 115 eyes showing myopic regression of more than -1 diopter or stromal haziness of more than grade 1(delayed steroid group; DSG), 0.1% fluorometholone was applied 4 times daily for 4 weeks, then tapered according to the planned schedule. 46.5% (100 eyes, non-steroid group;NSG) did not show the myopic regression nor stromal haziness without treatment of fluorometholone throughout the follow-up period. Uncorrected visual acuity, spherical equivalent and corneal haziness were evaluated 1, 2, 4, 8, 12, 24, 36 week after operation. 73%(73 eyes) of NSG and 27%(30 eyes) of DSG showed a myopia less than 6.0 diopters preoperatively. The proportion of male was 36% in NSG and 50.4% in DSG. 88.1% of male high myopia(>6.0 diopters) needed 0.1% fluorometholone, while 17.6% of female moderate and mild myopia(

Keyword

Corneal haziness; Excimer laser photorefractive keratectomy; Myopic regression; Topical steroid

MeSH Terms

Appointments and Schedules
Female
Fluorometholone
Follow-Up Studies
Humans
Incidence
Lasers, Excimer*
Male
Myopia
Photorefractive Keratectomy*
Visual Acuity
Fluorometholone