J Korean Ophthalmol Soc.
1995 May;36(5):787-792.
Evaluation of Chorioretinal Toxicity of Steroid after Intrachoroidal Injection in Rabbit
- Affiliations
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- 1Department of Ophthalmology, College of Medicine, Kyunghee University, Seoul, Korea.
Abstract
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To determine the ocular toxicity after intrachoroidal steroid injection in the rabbit eye, 0.15ml(40 mg/ml) triamcinolone acetonide, 0.15ml(40 mg/ml) methylprednisol one acetate and 0.15ml balanced salt solution(as controls) were injected into the choroid. The results were shown normal in fundus examination, electroretinography, and electron microscopy throughout the two weeks course of the experiment. From these result, it would appear that intrachoroidal 6 mg steroid injection demonstrated the lack of ocular toxicity.