J Korean Ophthalmol Soc.  1995 May;36(5):787-792.

Evaluation of Chorioretinal Toxicity of Steroid after Intrachoroidal Injection in Rabbit

Affiliations
  • 1Department of Ophthalmology, College of Medicine, Kyunghee University, Seoul, Korea.

Abstract

To determine the ocular toxicity after intrachoroidal steroid injection in the rabbit eye, 0.15ml(40 mg/ml) triamcinolone acetonide, 0.15ml(40 mg/ml) methylprednisol one acetate and 0.15ml balanced salt solution(as controls) were injected into the choroid. The results were shown normal in fundus examination, electroretinography, and electron microscopy throughout the two weeks course of the experiment. From these result, it would appear that intrachoroidal 6 mg steroid injection demonstrated the lack of ocular toxicity.

Keyword

Chorioretinal toxicity; Intrachoroidal needle insertion; Methylprednesolone; Pathology; Triamcinolone

MeSH Terms

Choroid
Electroretinography
Microscopy, Electron
Pathology
Triamcinolone
Triamcinolone Acetonide
Triamcinolone
Triamcinolone Acetonide
Full Text Links
  • JKOS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr