J Korean Ophthalmol Soc.  1993 Nov;34(11):1093-1100.

Histopathologic Findings after Experimental Penetrating Keratoplasty using Dacron-Gore-Tex(R) Combined Graft in Rabbits: Treatment of Corneal Perforation using Synthetic Materials. Report II

• Lee JK
• Choi KY
• Yoon BJ

Abstract

The purpose of this study is to evaluate the histopathologic findings after experimental penetrating keratoplasty using Dacron-Gore-Tex(R) combined graft in rabbits and the clinical efficacy of the treatment of corneal perforation using synthetic materials. Type A which used end to end fixation showed better results than that of type B which used intralamellar fixation and, however, complications and instability of graft occured in most eyes of both types. Type C which modified type B and reduced the thickness of intralamellar portion of graft showed relatively good results compared with type A and B, but there was still instability. Leakage from anterior chamber in early postoperative period prior to fiibrovascular invasion into graft was considered as the main cause of instability of graft. Therefore we performed type D which emphasized on preventing leakage, and well-maintained anterior chamber without extrusion of graft, that is, the best result among all 4 types was observed until 6 weeks postoperatively. Although further study is needed, we think that Dacron-Gore-Tex(R) combined graft can be a good substitute for the management of corneal perforation.

Keyword

Corneal perforation; Dacron; Fibrovascular invasion; Gore-Tex(R) Lekage

MeSH Terms

Anterior Chamber
Corneal Perforation*
Keratoplasty, Penetrating*
Polyethylene Terephthalates
Postoperative Period
Rabbits*
Transplants*
Polyethylene Terephthalates