J Korean Ophthalmol Soc.  1992 May;33(5):495-500.

Pupillary Dilatation with Mydriatics in Diabetic Retinopathy

• Jung BH
• Kim SY

Abstract

As the number of diabetic patient increases, it is important to manage diabetic retinopathy. Clinically sufficient pupillary dilatation should be obtained for fundoscopic examination and laser photocoagulation theraphy of diabetic patient but we experienced insufficient and delayed pupillary dilatation after instillation of mydriatics. In order to examine abnormality of pupillary dilatation and its relationship to the stage of diabetic retiniopathy, the course of pupillary diameter was measured with Haab's pupillometer after instillation of one drop of 1% Mydriacyl(R) and 2.5% Mydfrin(R) in 72 patients with diabetes mellitus (40-69 years old) and 11 normal controls (40-69 years old). The following results were obtained. After instillation of 1% Mydracy(R), the maximum pupillary diameter was smaller in diabetic retinopathy group than in controls. As the severity of diabetic retinopathy was increased, maximum pupillary diameter was decreased. After instillation of 2.5% Mydfrin(R), the delay of the average time to reach maximal mydriasis in diabetic group was larger than that in controls. This delay was proportional to the severity of diabetic retinopathy. Therefore it was considered that the abservation of the course of pupillary diameter after instillation of mydriatics would be useful for diagnosis of the severity of diabetic retinopathy.

Keyword

Diabetic retinopathy; 2.5% Mydfrin(R); 1% Mydriacyl(R)

MeSH Terms

Diabetes Mellitus
Diabetic Retinopathy*
Diagnosis
Dilatation*
Humans
Light Coagulation
Mydriasis
Mydriatics*
Mydriatics