J Korean Ophthalmol Soc.
1987 Aug;28(4):877-883.
Two Cases of Tuberous Sclerosis
- Affiliations
-
- 1Department of Ophthalmology, College of Medicine, Pusan National University, Pusan, Korea.
Abstract
- Retinal hamartomas are usually found in more than half of patients with ocular involvement of tuberous sclerosis. Morphologically, the retinal hamartomas have been divided into three types: type 1, the relatively flat, soft-appearing, and semitransparent lesions; type 2, elevated, nodular, and solid-appearing masses; and type 3, a combination of the two. In some instances, fundus contains a number of midpripheral depigmented lesions that appeared to be punched-out. The authors experienced two cases of tuberous sclerosis which consist of retinal hamartomas, skin lesions, and seizure. The first case was a 22-year-old man with all 3 types of retinal hamartomas and one punched-out lesion. The second case was a 19-year-old female with type 1 retinal hamartomas in both eyes. Retinal hamartomas showed varying degrees of diffuse fluorescein leakage according to the types from the capillaries within the tumors.
