Korean J Dermatol.
1997 Oct;35(5):997-1000.
A Case of Doxycycline-induced Phototoxicity
- Affiliations
-
- 1Department of Dermatology, College of Medicine, Gyeongsang National University, Chinju, Gyeongnam, Korea.
- 2Department of Chemistry, College of Teaching, Gyeongsang National University, Chinju, Gyeongnam, Korea.
Abstract
- We report a case of doxycycline-induced phototoxicity in a 62-years-old male. The patient, had erythematous macules and patches on sun-exposed areas. A Phototest revealed a marked decreased minimal erythemai. dose (MED) to UVA (MED(UNA)=-10J/cm2). Photopatch tests with 1%, 5% Doxycycline ointment were negative. An oral provocation test was performed, which showed a positive result with a decrease of MED to UVA (MED(UVA)= 20J/cm2). After the cessation of doxycycline, his skin lesioris were improved markedly with complete loss of photosensitivity.
