Korean J Otolaryngol-Head Neck Surg.  2003 Dec;46(12):1064-1069.

Clinical Analysis of the Laryngeal Leukoplakia

• Chung PS
• Jeong SK
• Lee JG
• Chung YW

Abstract

BACKGROUND AND OBJECTIVES
Leukoplakia is a descriptive term designating a white patch or plaque of the mucosa and must be complemented by histology. The aim of this study was to analyze the laryngeal leukoplakia clinically. MATERIALS AND METHOD: 48 patients were included from 1995 to 2001. All presented themselves with laryngeal leukoplakia in telescopic examination. The available medical record are age, sex, duration of smoking, histopathological finding, treatment and follow up result. RESULTS: The patients were composed of 46 males and 2 females. There were 7 patients (15%) with specific diagnostic lesion (polyps, lymphoma, tuberculosis, chronic inflammation and papilloma), 19 patients (40%) with simple hyperplasia or hyperkeratosis, 4 patients (8%) with mild dysplasia, 2 patients (4%) with moderate dysplasia, 2 patients (4%) with severe dysplasia, 2 patients (4%) with carcinoma in situ, and 1 patient (2%) with microinvasive carcinoma and 11 patients with invasive squamous cell carcinoma. Rebiopsy was performed to 10 cases during follow up period. CONCLUSION: The results of our study show that the leukoplakia was presented in 15% of all cases with specific diagnostic lesion and that the patient was treated according to their specific diagnosis. Almost all of the case with precancerous conditions were cured with cord stripping, cordectomy or radiation therapy.

Keyword

Leukoplakia; Larynx; Precancerous conditions

MeSH Terms

Carcinoma in Situ
Carcinoma, Squamous Cell
Complement System Proteins
Diagnosis
Female
Follow-Up Studies
Humans
Hyperplasia
Inflammation
Larynx
Leukoplakia*
Lymphoma
Male
Medical Records
Mucous Membrane
Precancerous Conditions
Smoke
Smoking
Tuberculosis
Complement System Proteins
Smoke