Clinical Investigation of Certain Plasma Hormones on Male Sexual and Reproductive Functions

Lee, Hee Yong; Kim, Tae Kyu; Han, Bung Ho

Abstract

Certain hormone values were evaluated on 207 subjects during the period from January 1983 to December 1983. These subjects were divided into the following 5 groups: Group I composed of 28 healthy men; Group AI, 83 patients with impotence; Group III, 60 patients with infertility; Group AV, 31 patients with hypogonadism; and Group V, 5 patients with intersex. Levels of plasma LH, FSH, testosterone and prolactin were measured by radioimmunoassay technique. Results were analysed and compared with those of control group. Conclusions were summarized as follows: 1. Mean values of plasma LH, FSH, and testosterone of Group I(control group)were 7.91mIU/ml, 11.29 mIU/ml, and 595.7ng/100ml, respectively. 2. In Group II, mean values of FSH were significantly decreased, but those of testosterone and prolactin were within normal ranges. 3. In Group III, mean values of plasma LH and FSH were significantly elevated but those of plasma testosterone were inversely decreased. Levels of plasma prolactin were within normal ranges. 4. Testicular histology taken from azoospermias revealed that most common findings were germ cell aplasia. 5. In Group IV, hypergonadotropic to hypogonadotrophic hypogonadism ratio was 1.4:1. Mean values of plasma LH and FSH were significantly elevated in hypergonadotropic hypogonadism, but decreased in hypogonadotrophic hypogonadism, Mean values of testosterone decreased in both groups 7. A reciprocal proportion was found between age and plasma testosterone levels in the patients with varicocele.