J Korean Ophthalmol Soc.  2002 Mar;43(3):492-497.

The Ocular Manifestations of the Korean Juvenile Rheumatoid Arthritis Children

Affiliations
  • 1Department of Ophthalmology, Seoul National University College of Medicine, Korea. ysyu@snu.ac.kr
  • 2Department of Pediatrics, Seoul National University College of Medicine, Korea.
  • 3Artificial Eye Center of Clinical Research Institute, Seoul National University Hospital, Korea.

Abstract

PURPOSE: To investigate the ocular findings, risk factors, and clinical outcomes in juvenile rheumatoid arthritis (JRA) patients.
METHODS
JRA patients were classified to polyarticular, pauciarticular and systemic-onset type. We retrospectively analyzed the incidence of uveitis, cataract, elevation of intraocular pressure, and compared them to the type of JRA, gender, the presence of HLA B27 and antinuclear antibody.
RESULTS
Acute uveitis in 14 patients (23.7%) of 59 patients manifested 20~37.5% evenly in JRA type except polyarticular rheumatoid factor positive type and systemic-onset type. Chronic uveitis occurred only in 2 pauciarticular type patients. In female, antinuclear antibody positive, HLA B27 positive and pauciarticular type the uveitis was more frequently occured. Cataract was occured in 7 patients (11 eyes, 10.2%), preceded by uveitis in 3 patients (3 eyes) and no history of uveitis in the others (8 eyes). The cataract surgery was performed in 3 patients (4 eyes) due to visual disturbance and then corrected visual acuities were more than 0.7 except one eye with band keratopathy.
CONCLUSIONS
This study suggests that the ocular examinations are regularly required in cases of female, the presence of antinuclear antibody and pauciarticular type of JRA patients. Cataract surgery combined with posterior chamber intraocular lens implantation can be done with a good visual results in cases of poor vision.

Keyword

Juvenile rheumatoid arthritis; Uveitis; Cataract; Female; ANA; HLA B27

MeSH Terms

Antibodies, Antinuclear
Arthritis, Juvenile*
Cataract
Child*
Female
Humans
Incidence
Intraocular Pressure
Lens Implantation, Intraocular
Retrospective Studies
Rheumatoid Factor
Risk Factors
Uveitis
Visual Acuity
Antibodies, Antinuclear
Rheumatoid Factor
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